Research in the Orwig laboratory focuses on stem cells, germ lineage development, fertility and infertility. Our progress investigating reproductive function in fertile individuals provides a basis for understanding the mechanisms of infertility caused by disease, medical treatments, genetic defects or aging. Infertility impacts one in seven couples in the United States and can have a devastating impact on relationships and emotional well-being. The Orwig lab is ideally located in Magee-Womens Research Institute and Magee-Womens Hospital of the University of Pittsburgh and is committed to translating lab bench discoveries to the clinic for diagnosis, prevention and treatment of infertility.
The Fertility Preservation Program of Pittsburgh is a multidisciplinary effort committed to:
The Genome Editing, Transgenic and Virus (GETV) Core of Magee-Womens Research Institute is dedicated to shepherding transgenic model projects, from vector design to the establishment and maintenance of valuable transgenic lines.
The core assists investigators by developing state-of-the-art strategies and assays to solve complex biological problems via transgenic research and molecular research.
The Molecular Genetics and Developmental Biology (MGDB) graduate program provides an exceptionally exciting and vigorous academic environment for highly motivated and qualified students to prepare for a rewarding career in biomedical research. The MGDB faculty span several departments and encompasses three broad areas of research:
Fundamental investigations of normal cell, tissue and organ system development provide a basis for understanding the origins of human disease and development of safe, effective treatments.